Sniffing Out Death With A Bioelectronic
Sniffing Out Death With A Bioelectronic
The compound is the
result of a bacterial reaction involving lysine, which is an amino acid
commonly found in various food products. A previous study has shown that a
receptor in zebrafish has an affinity for cadaverine.
To make this receptor in the laboratory, scientists have turned to Escherichia coli bacteria as a host cell because it can easily produce large quantities of proteins. However, the production of this receptor in E. coli has been a challenge because it needs to be embedded in a membrane.
In this study, a team of researchers led by Associate Professor Hong Seunghun at Seoul National University packaged the cadaverine receptor from the zebrafish into nanodiscs, which are water friendly, membrane-like structures.
The researchers then placed the receptor-containing nanodiscs in a special orientation on a carbon nanotube transistor, completing the bioelectronic noseThe researchers suggest that the detector could someday prove useful in natural disaster scenarios, to recover corpses for
To make this receptor in the laboratory, scientists have turned to Escherichia coli bacteria as a host cell because it can easily produce large quantities of proteins. However, the production of this receptor in E. coli has been a challenge because it needs to be embedded in a membrane.
In this study, a team of researchers led by Associate Professor Hong Seunghun at Seoul National University packaged the cadaverine receptor from the zebrafish into nanodiscs, which are water friendly, membrane-like structures.
The researchers then placed the receptor-containing nanodiscs in a special orientation on a carbon nanotube transistor, completing the bioelectronic noseThe researchers suggest that the detector could someday prove useful in natural disaster scenarios, to recover corpses for
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